ISSN 0021-3454 (print version)
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10
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vol 67 / October, 2024
Article

DOI 10.17586/0021-3454-2015-58-10-859-861

UDC 681.51

STRUCTURE AND ELEMENT BASE OF CLOSED-TYPE BLOOD ANALYZER

A. A. Margun
ITMO University, Saint Petersburg, 197101, Russian Federation; Institute for Problems in Mechanical Engineering of the Russian Academy of Sciences, Saint Petersburg, 199178, Russian Federation; Associate professor; Scientific Researcher


D. N. Bazylev
ITMO University, Saint Petersburg, 197101, Russian Federation; postgraduate


K. A. Zimenko
ITMO University, Saint Petersburg, 197101, Russian Federation; Senior Scientific Researcher


A. S. Kremlev
ITMO University, Saint Petersburg, 197101, Russian Federation; Associate professor


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Abstract. Functions of automatic closed type blood analyzer are defined; structure of such an analyzer is developed. The analyzer is expected to significantly improve the quality, reliability and reproducibility of the clinical research results, as well as to standardize and unify the process of research and to exclude the "human factor". Comparative analysis of the analyzer to be designed with analogues demonstrate that  automated systems for clinical diagnostics developed by domestic producers do not meet all requirements of the modern market, and foreign developments are highly specialized and do not allow to solve the whole complex of tasks in clinical research. Production of automated systems for immunosorbent assay is shown to be a relevant and promising task. The proposed block diagram was developed to provide implementation of the required functions within minimized weight and size parameters; an element base of the blood analyzer is selected. A reasonable choice of executive and measuring devices, the equipment flushing system, and reagents dispensing system is presented.
Keywords: automation system, blood analyzer, devices for clinical research, medical equipment

References:
  1. Syrygina E.P., Imel"baeva E. A., Gil"manov A.Zh., Abzalov R.R. Klinicheskaya laboratornaya diagnostika, 2007, no. 9, pp. 23a–23. (in Russ.)
  2. Shakirova E.M., Zemlyakova E.I. Prakticheskaya meditsina, 2011, no. 1(49), pp. 25–28. (in Russ.)
  3. Veronesi M.C., Gloria A., Panzani S., Sfirro M.P., Carluccio A., Contri A. Theriogenology, 2014, no. 2 (82), pp. 294–303. (in Russ.)
  4. Syryamkin V.I., Zhdanov D.S., Bureev A.Sh., Osipov A.Sh., Osipova A.Yu. Izv. vuzov. Priborostroenie, 2012, no. 2(55), pp. 61–63. (in Russ.)
  5. Tijssen P. Practice and theory of enzyme immunoassays. Amsterdam; New York, Elsevier, 1985.
  6. Kotani K., Minami T., Abe T., Sato J., Taniguchi N., Yamada T. Clinica Chimica Acta, 2014, no. 433, pp. 145–149.
  7. Ratzinger F., Schmetterer K.G., Haslacher H., Perkmann T., Belik S., Quehenberger P. Clinical Chemistry and Laboratory Medicine, 2014, no. 52 (8), pp. 1193–1202.
  8. Sharma P., Bhargava M., Sukhachev D., Datta S. Wattal C. International Journal of Laboratory Hematology, 2014, no. 36 (1), pp. 45–55.