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11
Issue
vol 67 / November, 2024
Article

DOI 10.17586/0021-3454-2021-64-8-674-679

UDC 616-71

GAS CHROMATOGRAPH FOR MEDICAL RESEARCH

N. I. Ivanova
Tver State Technical University; Department of Biotechnology, Chemistry and Standardization;


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Abstract. A photoionization generator – detector of gases and vapors is developed. The instrument design, principle of operation, and performance are discussed. The possibility of using the detector in a gas chromatograph with a capillary column, for example, for medical purposes (especially in respiratory diagnostics for detection of various diseases) is considered. The detector diagram is demonstrated, elements of the chromatograph are described in detail. Presented results of experiments confirm applicability of photoionization generator – detector in capillary gas chromatography for the analysis of liquid multicomponent media.
Keywords: chromatograph, photoionization detector, ultraviolet lamp, respiratory diagnostics, potential difference

References:
  1. Zelenin K.V. Sorosovskiy obrazovatel'nyy zhurnal, 1996, no. 11, pp. 20–26. (in Russ.)
  2. Stepanov E.V. Trudy IOFAN, 2005, vol. 61, рр. 5–47. (in Russ.)
  3. Bulanova A.V., Polyakova Yu.L. Khromatografiya v meditsine i biologii (Chromatography in Medicine and Biology), Samara, 2006, 116 р. (in Russ.)
  4. Patent RU 2523765, G01N27/64, Fotoionizatsionnyy detektor dlya gazoanaliticheskoy apparatury (Photoionization Detector for Gas Analytical Equipment), N.I. Evlanova, L.V. Ilyasov,. Priority 24.12.2012, Published. 20.07.2014, Bulletin 20. (in Russ.)
  5. Tkhorzhevsky V.P. Avtomaticheskiy analiz khimicheskogo sostava gazov (Automatic Analysis of the Chemical Composition of Gases), Moscow, 1969, 323 р. (in Russ.)
  6. Brazhnikov V.V. Detektory dlya khromatografii (Chromatography Detectors), Moscow, 1992, 320 р. (in Russ.)
  7. Ivanova N.I. Vestnik Tverskogo gosudarstvennogo tekhnicheskogo universiteta. Seriya "Tekhnicheskiye nauki", 2019, no. 3(3), pp. 79–88. (in Russ.)
  8. Patent RU64345, G01N27/67, Fotoionizatsionnyy detektor gazov i parov (Photoionization Detector of Gases and Vapors), N.I. Evlanova, L.V. Ilyasov, Priority 02.02.2010, Published 20.05.2010, Bulletin 14. (in Russ.)
  9. Patent RU 122179, G01N27/64, Fotoionizatsionnyy detektor gazov (Photoionization Detector of Gases), N.I. Evlanova, L.V. Ilyasov, Priority 22.06.2012, Published 20.11.2012, Bulletin 32. (in Russ.)
  10. Tsarev B.M. Kontaktnaya raznost' potentsialov (Contact Potential Difference), Moscow, 1959, 280 р. (in Russ.)
  11. Lukash S.I. Computer tools, networks and systems, 2010, no. 9, pp. 62–71. (in Russ.)
  12. Chuikova K.I., Kistenev Yu.V., Gomboeva S.S. Bulletin of Siberian Medicine, 2012, no. 6, pp. 178–185. (in Russ.)
  13. Evlanova N.I., Ilyasov L.V. Vestnik Tverskogo gosudarstvennogo tekhnicheskogo universiteta, 2013, no. 2(24), pp. 45-49. (in Russ.)
  14.  Evlanova N.I. Matematicheskiye metody v tekhnike i tekhnologiyakh (Mathematical Methods in Engineering and Technology), Abstracts of. XXIII International Scientific Conference, Smolensk, 2010, рр. 110–111. (in Russ.)
  15. Vilesov F.I. Sov. Phys. Usp., 1964, no. 6, pp. 888–929, DOI: 10.1070/PU1964v006n06ABEH003617.